Frequently Asked Questions
How do I contact Wren Laboratories?
USA Email: firstname.lastname@example.org
USA Phone: 203-208-3464
London Email: email@example.com
London Phone: +44 (0) 7454101915
How do I order a test?
To order a test, you first need to register on the website. Please go to www.wrenlaboratories.com and click on the “Order a NETest” button. This will take you to a registration page. Please fill in your details including your address, to which the kit will be sent. Your email will be your login name. You will be asked to provide your own password. Please save both as these are user specific and are required for ordering the test. After you have set-up your account you will receive a registration confirmation email from us within 24-72 hrs. This will include a specific password (a mixture of numbers and letters) that we will provide you. You will need this password to open the patient reports. Once you have received confirmation you can order the test.
How do I order a test after registering as a Wren Laboratories user?
At www.wrenlaboratories.com enter the ordering site and login using your email and the password you chose at registration. This will open a page with options for ordering the NETest or the PPQ/PRRedicTor test. Chose the test and follow the instructions regarding patient information and payment. Please fill in all the required patient information. This is essential for the generation of an accurate test report. Once you have finished ordering the test online, we will email you a requisition form with your order as a .pdf. Please print out the order form which will include the test ordered, your details and the patient’s information. This form needs to be signed by you and included with the patient sample. It has a bar code (top right) that links the order to the sample and patient’s details. We will send you a kit (to the address you provided on registration) with the blood collection tube and instructions for collecting the blood sample and sending it to the laboratory for analysis. If you require tracking information for the kit, please request this directly from us and we will provide it.
Can I order both a NETest and PPQ/PRRedicTor test for the same patient at the same time?
Yes, once you have finished ordering the NETest, you can then add the PPQ/PRRedicTor test. Please ensure the tumour grade is included when you order the PPQ. We will send you a separate email with a requisition form for the PPQ. Please note, you only need to collect one blood tube for both the NETest and PPQ test.
Is the NETest CE marked?
The NETest is not currently CE marked and is made available exclusively on Research Use Only basis.
KIT DELIVERY AND STORAGE
What can I do if I haven’t received my kit delivery?
If you haven’t received your package from us, please contact us from any of the ways above.
Can I change the address to which the kit is sent after I submit an order?
Unfortunately, as we try to ship the kit within 24hrs to the provided address, we cannot change the shipment address. Please contact our team if you need to re-order the test.*
*Potentially subject to a shipping fee
How can the kit be stored?
Once you receive your kit package from us, please store at room temperature until the blood collection. The Wren RNA stabilization tube is stable and can be used until the tube expires (typically 6-12 months). Please check the tube label.
BLOOD COLLECTION AND SENDOUT
How should the blood be collected and sent to the lab?
The blood should be drawn into the provided Wren RNA stabilization tube. Please write the last 3 digits of the sample ID on the tube before collecting the blood. The SAMPLE ID is on the requisition form (top right hand corner). Approximately 2ml of blood is collected. Once the tube is full, gently invert 10 times. The tube can be kept at room temperature until you send the sample. Please send the sample on the same or on next day to the laboratory using the kit provided. The tube does not need to be frozen. Please remember to include the order form that you signed in the kit.
If you are conducting a study and are collecting several patient samples over a period of time and want to batch send the samples in one delivery, please freeze all collected tubes in a -80°C freezer (NOT a normal refrigerator freezer). Samples should be frozen within 2 hrs. of collection. Once sufficient samples are collected (e.g., 20), please defrost (leave the tubes for 30 minutes at room temperature) and then send to the laboratory by courier. The samples do not need to be sent frozen or on ice. They can be sent at room temperature using the kit box provided.
Please click here to download the collection protocol
I have lost the collection instructions/ patient form etc.
If you have misplaced the instructions for collection or the kit please contact us. If you have misplaced the order form, please check your emails. You will find this as an email from Wren Laboratories. If you cannot find the requisition in your email inbox, please contact us directly.
How is data processed?
The blood sample is processed and the neuroendocrine tumour gene expression quantified in laboratories in either the US or in the UK. The individual target gene data is processed using secure servers and proprietary algorithm analyses. The final output is provided in a report, as a score from 0-100 where 0 is the lowest risk and 100 is the high risk.
How will I receive the result?
The result will be sent to you, the ordering physician, via secure email. The results are sent as a password protected PDF. You will receive an email with a .pdf attached. Click on the attachment and your email program will open the .pdf document which is the report. You will be asked for the password. This is the 36 digit/number password we sent you via email after you registered. Please enter it and the report will open. You can save and print the report. Once the report is saved (e.g., to a patient folder) it remains password protected. If your patient requires a copy of their results, please send a hardcopy to them.
The NETest report includes a number which is your patient’s score. This ranges from 0 to 100. Scores from 0-20 fall into the normal category. Scores that range 21-40 fall into the stable disease category. Scores from 41-100 fall into the progressive disease category. Literature about the NETest, how it was developed and how it provides clinical utility is included in your report. Click here for a sample of the NETest report.
The PPQ/PRRedicTor report includes a graphic with your patient’s risk of progressing after PRRT and whether the patient is predicted to respond or not to respond to PRRT. Details about the PPQ, how it was developed and how it provides clinical utility is included on the report. Click here for a sample of a PPQ/PRRedicTor report.
How accurate are the results?
The NETest score has been validated in thousands of patients and published in over 20 articles. The overall accuracy as a diagnostic is 96%. Articles about the NETest are included on the Wren website. To access them, click here.
The PPQ/PRRedicTor test has been recently developed and demonstrated to be 94-99% accurate for predicting a response to PRRT. Articles about the PPQ test are included on the Wren website. To access them, click here and click on the PRRedicTor tab.
Where can I leave feedback?